Syn2^tm1Pggd
Targeted Allele Detail

Summary

• Symbol: Syn2^tm1Pggd
• Name: synapsin II; targeted mutation 1, Paul Greengard
• MGI ID: MGI:3045984
• Synonyms: Syn2^tm1Kao
• Gene: Syn2 Location: Chr6:115111863-115258967 bp, + strand Genetic Position: Chr6, 53.2 cM, cytoband F
• Alliance: Syn2^tm1Pggd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:91113
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exon1 was replaced with a neomycin cassette inserted by homologous recombination. (J:91115)

Disease models

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Syn2 Mutation: 24 strains or lines available

References

• Original: J:91113 Ferreira A, et al., Distinct roles of synapsin I and synapsin II during neuronal development. Mol Med. 1998 Jan;4(1):22-8
• All: 43 reference(s)