Tg(Pax2-cre)1Akg
Transgene Detail

Summary

• Symbol: Tg(Pax2-cre)1Akg
• Name: transgene insertion 1, Andrew K Groves
• MGI ID: MGI:3046196
• Synonyms: Pax2-Cre
• Transgene: Tg(Pax2-cre)1Akg Location: unknown
• Alliance: Tg(Pax2-cre)1Akg page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Pax2-cre)1Akg expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Pax2

• Mutation details: A 121kb segment of the Pax2 gene which included 101 kb of sequence upstream of exon1, all of exons 1 and 2, part of exon 3, as well as introns 1 and 2, was modified by the insertion of IRES-cre into exon 2. Cre expression was demonstrated in the otic placode starting at the 6-7 somite stage. Cre expression also occurred in the midbrain-hindbrain boundary and the embryonic kidney. Two founders showed germline transmission of cre, and the line that displayed stronger cre mRNA expression was designated by MGI as line 1. (J:89784)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Pax2 (species not specified) Summary of all recombinase alleles driven by Pax2. Comparative matrix view of recombinase activities

Expression

In Mice Carrying this Mutation:

198 assay results 9 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available

References

• Original: J:89784 Ohyama T, et al., Generation of Pax2-Cre mice by modification of a Pax2 bacterial artificial chromosome. Genesis. 2004 Apr;38(4):195-9
• All: 135 reference(s)