Fabp2^tm1Mto
Targeted Allele Detail

Summary

• Symbol: Fabp2^tm1Mto
• Name: fatty acid binding protein 2, intestinal; targeted mutation 1, Matthew J Toth
• MGI ID: MGI:3046293
• Synonyms: Fabpi^-
• Gene: Fabp2 Location: Chr3:122688721-122693155 bp, + strand Genetic Position: Chr3, 53.74 cM
• Alliance: Fabp2^tm1Mto page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:64975
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin selection cassette replaced part of exon 1. Northern blot, RT-PCR and western blot analysis confirmed the lack of encoded transcript and protein, respectively. (J:64975)

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fabp2 Mutation: 12 strains or lines available

References

• Original: J:64975 Vassileva G, et al., The intestinal fatty acid binding protein is not essential for dietary fat absorption in mice. FASEB J. 2000 Oct;14(13):2040-6
• All: 3 reference(s)