Hprt1^{tm1(CMV-cre)Brd}
Targeted Allele Detail

Summary

• Symbol: Hprt1^{tm1(CMV-cre)Brd}
• Name: hypoxanthine phosphoribosyltransferase 1; targeted mutation 1, Allan Bradley
• MGI ID: MGI:3046308
• Synonyms: Hprt^{Tg(CMV-Cre)Brd}
• Gene: Hprt1 Location: ChrX:52077014-52110536 bp, + strand Genetic Position: ChrX, 29.31 cM, cytoband A6
• Alliance: Hprt1^{tm1(CMV-cre)Brd} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:75278
• Parent Cell Line: AB1 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1⁺

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Hprt1^{tm1(CMV-cre)Brd} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  virus	CMV

• Mutation details: An expression cassette containing a CMV promoter driving Cre recombinase expression was inserted into exon 3 of the gene. (J:75278)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	CMV (virus) Summary of all recombinase alleles driven by CMV.

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hprt1 Mutation: 1279 strains or lines available

References

• Original: J:75278 Su H, et al., A targeted X-linked CMV-Cre line. Genesis. 2002 Feb;32(2):187-8
• All: 25 reference(s)