Pias4tm1Hwu
Targeted Allele Detail
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Symbol: |
Pias4tm1Hwu |
Name: |
protein inhibitor of activated STAT 4; targeted mutation 1, Hong Wu |
MGI ID: |
MGI:3046514 |
Synonyms: |
Piasy- |
Gene: |
Pias4 Location: Chr10:80989795-81003554 bp, - strand Genetic Position: Chr10, 39.72 cM, cytoband C1
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Alliance: |
Pias4tm1Hwu page
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Germline Transmission: |
Earliest citation of germline transmission:
J:91085
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
129
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: The majority of the coding region, exons 3 - 11, was replaced with a neo gene via homologous recombination. RT-PCR and western blot analysis confirmed the absence on RNA and protein expression in homozygous mutants
(J:91085)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Pias4 Mutation: |
25 strains or lines available
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Original: |
J:91085 Wong KA, et al., Protein inhibitor of activated STAT Y (PIASy) and a splice variant lacking exon 6 enhance sumoylation but are not essential for embryogenesis and adult life. Mol Cell Biol. 2004 Jun;24(12):5577-86 |
All: |
2 reference(s) |
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