Tg(tetO-cre)1Lin
Transgene Detail

Summary

• Symbol: Tg(tetO-cre)1Lin
• Name: transgene insertion 1, Jonas Lindeberg
• MGI ID: MGI:3046554
• Synonyms: tetO-Cre
• Transgene: Tg(tetO-cre)1Lin Location: unknown
• Alliance: Tg(tetO-cre)1Lin page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Tg(tetO-cre)1Lin expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  bacteria	tetO

• Mutation details: This transgene consists of a tetracycline responsive promoter driving the expression of Cre recombinase. The transgene is not expressed in the absence of a transactivating transcription factor (tTA). When this transgene is present in conjunction with the expression of tTA, Cre recombinase activity is found only where tTA is expressed, and only when doxycycline is not present. (J:82535)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	tetO (bacteria) Summary of all recombinase alleles driven by tetO.

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:82535 Lindeberg J, et al., Timing the doxycycline yields different patterns of genomic recombination in brain neurons with a new inducible Cre transgene. J Neurosci Res. 2002 Apr 15;68(2):248-53
• All: 5 reference(s)