Hoxb1^tm7Mrc
Targeted Allele Detail

Summary

• Symbol: Hoxb1^tm7Mrc
• Name: homeobox B1; targeted mutation 7, Mario R Capecchi
• MGI ID: MGI:3046794
• Synonyms: Hoxb1^C
• Gene: Hoxb1 Location: Chr11:96256578-96259082 bp, + strand Genetic Position: Chr11, 59.86 cM
• Alliance: Hoxb1^tm7Mrc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:91364
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The entire coding region was flanked with lox511 sites following the excision of a floxed neo by crossing with deleter strain expressing Flp in the germ line. Southern blot confirmed recombination. (J:91364)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hoxb1 Mutation: 24 strains or lines available

References

• Original: J:91364 Arenkiel BR, et al., Hoxb1 functions in both motoneurons and in tissues of the periphery to establish and maintain the proper neuronal circuitry. Genes Dev. 2004 Jul 1;18(13):1539-52
• All: 1 reference(s)