Or4e5^tm1(cre)Rax
Targeted Allele Detail

Summary

• Symbol: Or4e5^tm1(cre)Rax
• Name: olfactory receptor family 4 subfamily E member 5; targeted mutation 1, Richard Axel
• MGI ID: MGI:3046829
• Synonyms: MOR28-IRES-Cre
• Gene: Or4e5 Location: Chr14:52727392-52733152 bp, - strand Genetic Position: Chr14, 26.97 cM
• Alliance: Or4e5^tm1(cre)Rax page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:90717
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Or4e5^tm1(cre)Rax expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Or4e5 (MGI:3031341)

• Mutation details: A cassette containing an IRES-Cre and FRT-flanked neo was inserted 50 bp upstream of the stop codon. Southern blot confirmed recombination. Immunohistochemistry indicated that cells expressing the endogenous gene also expressed Cre. (J:90717)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Or4e5 (mouse) Summary of all recombinase alleles driven by Or4e5. Alliance mouse Or4e5 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Or4e5 Mutation: 20 strains or lines available

References

• Original: J:90717 Shykind BM, et al., Gene switching and the stability of odorant receptor gene choice. Cell. 2004 Jun 11;117(6):801-15
• All: 6 reference(s)