Tg(Lefty2-cre)21bHmd
Transgene Detail

Summary

• Symbol: Tg(Lefty2-cre)21bHmd
• Name: transgene insertion 21b, Hiroshi Hamada
• MGI ID: MGI:3046967
• Synonyms: lefty2-Cre, Tg(Ebaf-cre)21bHmd
• Transgene: Tg(Lefty2-cre)21bHmd Location: unknown
• Alliance: Tg(Lefty2-cre)21bHmd page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Lefty2-cre)21bHmd expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Lefty2

• Mutation details: The 5.5 kb upstream region of Ebaf was linked to a Cre cassette. In this transgene, the promoter specifically directed cre expression in the epiblast and its derivatives between E5.5 and E8.0. (J:69593)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Lefty2 (species not specified) Summary of all recombinase alleles driven by Lefty2. Comparative matrix view of recombinase activities

Expression

In Mice Carrying this Mutation:

5 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:69593 Yamamoto M, et al., The transcription factor FoxH1 (FAST) mediates Nodal signaling during anterior-posterior patterning and node formation in the mouse. Genes Dev. 2001 May 15;15(10):1242-56
• All: 4 reference(s)