Zdhhc8^tm1Kara
Targeted Allele Detail

Summary

• Symbol: Zdhhc8^tm1Kara
• Name: zinc finger, DHHC domain containing 8; targeted mutation 1, Maria Karayiorgou
• MGI ID: MGI:3047084
• Synonyms: Zdhhc8^-
• Gene: Zdhhc8 Location: Chr16:18038617-18053000 bp, - strand Genetic Position: Chr16, 11.29 cM
• Alliance: Zdhhc8^tm1Kara page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:91131
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A floxed pACN cassette that includes a neo replaced exons 2-11. Southern blot showed successful recombination and brain RT-PCR indicated lack of transcript in mutants. (J:91131)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zdhhc8 Mutation: 26 strains or lines available

References

• Original: J:91131 Mukai J, et al., Evidence that the gene encoding ZDHHC8 contributes to the risk of schizophrenia. Nat Genet. 2004 Jul;36(7):725-31
• All: 5 reference(s)