Or8a1^{tm14(Adrb2)Mom}
Targeted Allele Detail

Summary

• Symbol: Or8a1^{tm14(Adrb2)Mom}
• Name: olfactory receptor family 8 subfamily A member 1; targeted mutation 14, Peter Mombaerts
• MGI ID: MGI:3047219
• Synonyms: b2AR->M71-IRES-taulacZ, Beta2AR->M71-LacZ
• Gene: Or8a1 Location: Chr9:37641273-37642357 bp, - strand Genetic Position: Chr9, 20.8 cM
• Alliance: Or8a1^{tm14(Adrb2)Mom} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:91160
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Or8a1^{tm14(Adrb2)Mom} expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  mouse	Adrb2 (MGI:87938)

• Mutation details: The coding region was replaced with Adrb2 and IRES-taulacZ. Antibody staining indicated Adrb2 expression in cilia, cell bodies and axons of olfactory sensory neurons. (J:91160)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Or8a1 Mutation: 69 strains or lines available

References

• Original: J:91160 Feinstein P, et al., Axon guidance of mouse olfactory sensory neurons by odorant receptors and the beta2 adrenergic receptor. Cell. 2004 Jun 11;117(6):833-46
• All: 2 reference(s)