Tg(UAS-Shh)1Rth
Transgene Detail

Summary

• Symbol: Tg(UAS-Shh)1Rth
• Name: transgene insertion 1, David H Rowitch
• MGI ID: MGI:3047220
• Synonyms: UAS-Shh
• Transgene: Tg(UAS-Shh)1Rth Location: unknown
• Alliance: Tg(UAS-Shh)1Rth page

Transgene origin

• Strain of Origin: (C57BL/6J x CBA/J)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(UAS-Shh)1Rth expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Shh (MGI:98297)

• Mutation details: This transgene consists a yeast upstream activating sequence (UAS) driving expression of a full-length murine Shh cDNA. Expression of this transgene is dependent on GAL4 expression. Only one line in which Shh expression was promoted in response to GAL4 expression in the CNS was generated. (J:57948)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:57948 Rowitch DH, et al., Sonic hedgehog regulates proliferation and inhibits differentiation of CNS precursor cells. J Neurosci. 1999 Oct 15;19(20):8954-65
• All: 2 reference(s)