Or8a1^{tm16(Or8a1b/Or1f19)Mom}
Targeted Allele Detail

Summary

• Symbol: Or8a1^{tm16(Or8a1b/Or1f19)Mom}
• Name: olfactory receptor family 8 subfamily A member 1; targeted mutation 16, Peter Mombaerts
• MGI ID: MGI:3047222
• Synonyms: MOR23/M72/MOR23->M71GFP, MOR23/M72/MOR23->M71-IRES-tauGFP, Or8a1^{tm16(Olfr160/Olfr161)Mom}
• Gene: Or8a1 Location: Chr9:37641273-37642357 bp, - strand Genetic Position: Chr9, 20.8 cM
• Alliance: Or8a1^{tm16(Or8a1b/Or1f19)Mom} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:91160
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Inserted expressed sequence, Reporter)
• Mutations: Insertion, Intragenic deletion
• Or8a1^{tm16(Or8a1b/Or1f19)Mom} expresses 2 genes
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  mouse	Or1f19 (MGI:3032605)	amino acids 215-309
  mouse	Or8a1b (MGI:1931271)	amino acids 128-214

• Mutation details: The coding sequence was replaced by sequence encoding amino acids 1-127 of Olfr161, amino acids 128-214 of Olfr160 and amino acids 215-309 of Olfr161, followed by an IRES-tauGFP. (J:91160)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Or8a1 Mutation: 69 strains or lines available

References

• Original: J:91160 Feinstein P, et al., Axon guidance of mouse olfactory sensory neurons by odorant receptors and the beta2 adrenergic receptor. Cell. 2004 Jun 11;117(6):833-46
• All: 1 reference(s)