Or8a1^tm19Mom
Targeted Allele Detail

Summary

• Symbol: Or8a1^tm19Mom
• Name: olfactory receptor family 8 subfamily A member 1; targeted mutation 19, Peter Mombaerts
• MGI ID: MGI:3047225
• Synonyms: RFP->M71iM71iGFP, RFP->M71-IRES-M71-IRES-tauGFP
• Gene: Or8a1 Location: Chr9:37641273-37642357 bp, - strand Genetic Position: Chr9, 20.8 cM
• Alliance: Or8a1^tm19Mom page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:91160
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Hypomorph, Reporter)
• Mutation: Insertion
• Mutation details: The coding region was replaced with RFP and IRES-Olfr151-IRES-tauGFP. Both red and green fluorescence was detected in dorsal epithelium cell bodies and dendrites. This allele is putatively hypomorphic, though a lack of antibodies prevents measuring of protein levels. (J:91160)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Or8a1 Mutation: 69 strains or lines available

References

• Original: J:91160 Feinstein P, et al., Axon guidance of mouse olfactory sensory neurons by odorant receptors and the beta2 adrenergic receptor. Cell. 2004 Jun 11;117(6):833-46
• All: 2 reference(s)