Or8a1^tm20Mom
Targeted Allele Detail

Summary

• Symbol: Or8a1^tm20Mom
• Name: olfactory receptor family 8 subfamily A member 1; targeted mutation 20, Peter Mombaerts
• MGI ID: MGI:3047227
• Synonyms: M71(deltaM71)-IRES-taulacZ
• Gene: Or8a1 Location: Chr9:37641273-37642357 bp, - strand Genetic Position: Chr9, 20.8 cM
• Alliance: Or8a1^tm20Mom page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:91160
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The 3rd bp (G) from the initiation methionine was deleted. No upstream ATGs were created in-frame, leaving the next potential ATG in the coding region at position 115, which would result in a protein truncated by 38 amino acids. An IRES-taulacZ was incorporated downstream of the coding sequence. (J:91160)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Or8a1 Mutation: 69 strains or lines available

References

• Original: J:91160 Feinstein P, et al., Axon guidance of mouse olfactory sensory neurons by odorant receptors and the beta2 adrenergic receptor. Cell. 2004 Jun 11;117(6):833-46
• All: 1 reference(s)