Tg(EIF1AX-Il31ra)1Jagr
Transgene Detail

Summary

• Symbol: Tg(EIF1AX-Il31ra)1Jagr
• Name: transgene insertion 1, Jane A Gross
• MGI ID: MGI:3047472
• Synonyms: Tg(EIF1AX-Il31ra)1Jagr
• Transgene: Tg(EIF1AX-Il31ra)1Jagr Location: unknown
• Alliance: Tg(EIF1AX-Il31ra)1Jagr page

Transgene origin

• Strain of Origin: (C57BL/6 x C3H)F2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(EIF1AX-Il31ra)1Jagr expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Il31ra (MGI:2180511)

• Mutation details: This transgene consists of the human EIF1AX promoter driving expression of a mouse Il31 cDNA with a rat insulin II intron and a human growth hormone polyadenylation signal 5' or 3' to enhance expression. Serum concentration of IL31RA is 0.3 - 1.1 ng/ml (J:91124)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:91124 Dillon SR, et al., Interleukin 31, a cytokine produced by activated T cells, induces dermatitis in mice. Nat Immunol. 2004 Jul;5(7):752-60
• All: 2 reference(s)