Tg(KRT5-cre)5132Jlj
Transgene Detail

Summary

• Symbol: Tg(KRT5-cre)5132Jlj
• Name: transgene insertion 5132, Jose Luis Jorcano
• MGI ID: MGI:3050065
• Synonyms: BK5-Cre, K5^cre, K5 Cre, K5-Cre, K5Cre, K5Cre 5132, K5Cre5132, Tg.K5Cre, Tg(KRT5-cre)1Armz, Tg(KRT5-cre)1Jlj
• Transgene: Tg(KRT5-cre)5132Jlj Location: unknown
• Alliance: Tg(KRT5-cre)5132Jlj page

Transgene origin

• Strain of Origin: (C57BL/6J x DBA/2J)F2

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(KRT5-cre)5132Jlj expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  cattle	KRT5 (281268)

• Mutation details: This transgene consists of bovine KRT5 regulatory elements driving the expression of a nis-cre gene. A single copy of the transgene is present in this line. Cre expression is seen in the stratified epithelium. When the transgene is present in females ubiquitous cre mediated recombination occurs in all offspring independent of inheritance of the cre-transgene. (J:89783)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	KRT5 (cattle) Summary of all recombinase alleles driven by KRT5. Comparative matrix view of recombinase activities

Disease models

Expression

In Mice Carrying this Mutation:

69 assay results 4 RNA-Seq or microarray experiment(s)

Tumor Data

List all tumor models in MMHCdb carrying Tg(KRT5-cre)5132Jlj

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:89783 Ramirez A, et al., A keratin K5Cre transgenic line appropriate for tissue-specific or generalized Cre-mediated recombination. Genesis. 2004 May;39(1):52-7
• All: 134 reference(s)