Ntrk2^tm1Jom
Targeted Allele Detail

Summary

• Symbol: Ntrk2^tm1Jom
• Name: neurotrophic tyrosine kinase, receptor, type 2; targeted mutation 1, James O McNamara
• MGI ID: MGI:3050229
• Synonyms: Trkb^flox
• Gene: Ntrk2 Location: Chr13:58954383-59281784 bp, + strand Genetic Position: Chr13, 31.2 cM
• Alliance: Ntrk2^tm1Jom page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:91467
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exon 1, which encodes the signal peptide and the first 40 amino acids of the N terminus, was flanked with 2 loxp sites. (J:91467)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ntrk2 Mutation: 66 strains or lines available

References

• Original: J:91467 He XP, et al., Conditional deletion of TrkB but not BDNF prevents epileptogenesis in the kindling model. Neuron. 2004 Jul 8;43(1):31-42
• All: 28 reference(s)