Eno1^{Gt(ROSABetageo)1Ev}
Gene trapped Allele Detail

Summary

• Symbol: Eno1^{Gt(ROSABetageo)1Ev}
• Name: enolase 1, alpha non-neuron; gene trap 1, Martin Evans
• MGI ID: MGI:3050549
• Synonyms: GTE.2A4
• Gene: Eno1 Location: Chr4:150321178-150333336 bp, + strand Genetic Position: Chr4, 81.24 cM
• Alliance: Eno1^{Gt(ROSABetageo)1Ev} page

Mutation origin

• Mutant Cell Line: GTE.2A4
• Germline Transmission: Earliest citation of germline transmission: J:48375
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: ROSABetageo Vector Type: gene trap
• Mutation details: A gene trap vector inserted into the first intron of the gene. A fusion transcript containing the lacZ/neo genes from the inserted vector was expressed from this allele. Beta-galactosidase was detectable in embryonic mesoderm and adult testis. (J:48375)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Eno1 Mutation: 63 strains or lines available

Notes

ES cell line = CCE.1B

References

• Original: J:48375 Couldrey C, et al., Disruption of murine alpha-enolase by a retroviral gene trap results in early embryonic lethality. Dev Dyn. 1998 Jun;212(2):284-92
• All: 1 reference(s)