lsgd9a
Chemically induced Allele Detail

Summary

• Symbol: lsgd9a
• Name: late spermiogenesis defective 9a; male sterility, John Schimenti
• MGI ID: MGI:3050653
• Gene: lsgd9a Location: unknown Genetic Position: Chr2, Syntenic
• Alliance: lsgd9a page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Undefined
• Mutation details: Male mice were treated with ENU and mated with C3HeB/FeJ females. First generation males were again mated to C3H females and 2nd generation females were backcrossed to generation 1 males to produce the 3rd generation. The mutation was identified in a screen of the 3rd generation for male fertility. (J:86161)
• Inheritance: Recessive

Phenotypes

Key:

hm	homozygous	ht	heterozygous	tg	involves transgenes	√	phenotype observed
cn	conditional genotype	cx	complex: > 1 genome feature	ot	other: hemizygous, indeterminate,...	N	normal phenotype

Genotype/
Background:

	Allelic Composition	Genetic Background	Cell Line(s)
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hm1	lsgd9a/lsgd9a	involves: C3HeB/FeJ * C57BL/6

Phenotypes:

Affected Systems	hm1
show or hide all annotated terms Sex:
reproductive system	√
abnormal spermatogenesis	√
male infertility	√

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any lsgd9a Mutation: 0 strains or lines available

References

• Original: J:86161 Ward JO, et al., Toward the genetics of mammalian reproduction: induction and mapping of gametogenesis mutants in mice. Biol Reprod. 2003 Nov;69(5):1615-25
• All: 1 reference(s)