Timeless^tm1Rep
Targeted Allele Detail

Summary

• Symbol: Timeless^tm1Rep
• Name: timeless circadian clock 1; targeted mutation 1, Steven M Reppert
• MGI ID: MGI:3051143
• Gene: Timeless Location: Chr10:128067934-128088810 bp, + strand Genetic Position: Chr10, 76.49 cM
• Alliance: Timeless^tm1Rep page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:63669
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin selection cassette replaced coding sequence after codon 178. A reduced amount of encoded protein was detected in heterozygous animals. (J:63669)

Expression

In Mice Carrying this Mutation:

1 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Timeless Mutation: 62 strains or lines available

References

• Original: J:63669 Gotter AL, et al., A time-less function for mouse timeless. Nat Neurosci. 2000 Aug;3(8):755-6
• All: 1 reference(s)