Tg(MMTVTGFA)257Rjc
Transgene Detail

Summary

• Symbol: Tg(MMTVTGFA)257Rjc
• Name: transgene insertion 257, Robert J Coffey
• MGI ID: MGI:3051514
• Transgene: Tg(MMTVTGFA)257Rjc Location: unknown
• Alliance: Tg(MMTVTGFA)257Rjc page

Transgene origin

• Strain of Origin: (C57BL/6 x DBA/2)F2

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: This transgene contains the MMTV (mouse mammary tumor virus) LTR and the normal allele of the human TGFA (transforming growth factor alpha) gene. The vector also contains exons 2 and 3 of the rabbit beta-globin gene. (J:28453)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Tumor Data

List all tumor models in MMHCdb carrying Tg(MMTVTGFA)257Rjc

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

Lines 29, 64, and 254 were also produced.

References

• Original: J:28453 Matsui Y, et al., Development of mammary hyperplasia and neoplasia in MMTV-TGF alpha transgenic mice. Cell. 1990 Jun 15;61(6):1147-55
• All: 1 reference(s)