Socs1^tm1Jni
Targeted Allele Detail

Summary

• Symbol: Socs1^tm1Jni
• Name: suppressor of cytokine signaling 1; targeted mutation 1, James N Ihle
• MGI ID: MGI:3051623
• Synonyms: Socs1^-, SOCS-1 KO
• Gene: Socs1 Location: Chr16:10601672-10603400 bp, - strand Genetic Position: Chr16, 5.81 cM
• Alliance: Socs1^tm1Jni page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:57475
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• The entire coding sequence was deleted by the targeting construct. (J:57475)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Socs1 Mutation: 30 strains or lines available

References

• Original: J:57475 Marine JC, et al., SOCS1 deficiency causes a lymphocyte-dependent perinatal lethality. Cell. 1999 Sep 3;98(5):609-16
• All: 31 reference(s)