Hexim1^tm1Maqs
Targeted Allele Detail

Summary

• Symbol: Hexim1^tm1Maqs
• Name: hexamethylene bis-acetamide inducible 1; targeted mutation 1, M A Q Siddiqui
• MGI ID: MGI:3052225
• Synonyms: CLP-1^-, Cpl1^tm1Maqs
• Gene: Hexim1 Location: Chr11:103007151-103010551 bp, + strand Genetic Position: Chr11, 66.71 cM
• Alliance: Hexim1^tm1Maqs page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:92209
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin resistance gene replaced the coding exon. Northern blot of livers indicated lack of transcript in mutant mice. (J:92209)

Expression

In Mice Carrying this Mutation:	47 assay results
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hexim1 Mutation: 10 strains or lines available

References

• Original: J:92209 Huang F, et al., Ablation of the CLP-1 gene leads to down-regulation of the HAND1 gene and abnormality of the left ventricle of the heart and fetal death. Mech Dev. 2004 Jun;121(6):559-72
• All: 9 reference(s)