Tg(Cyp1a1-cre)1Dwi
Transgene Detail

Summary

• Symbol: Tg(Cyp1a1-cre)1Dwi
• Name: transgene insertion 1, Douglas J Winton
• MGI ID: MGI:3052655
• Synonyms: Ah-cre, AhCre, Cre^CYP1A1
• Transgene: Tg(Cyp1a1-cre)1Dwi Location: unknown
• Alliance: Tg(Cyp1a1-cre)1Dwi page

Transgene origin

• Strain of Origin: (C57BL/6 x CBA)F1

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: beta-naphthoflavone
• Mutation: Insertion
• Tg(Cyp1a1-cre)1Dwi expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  rat

  Cyp1a1 (24296)

  Cyp1a1

  (MGI:88588)

• Mutation details: The rat Cyp1a1 promoter drives the expression of cre recombinase. Halogenated aromatic hydrocarbon inducible cre expression is seen in multiple tissues. Four lines were generated but only one was characterized in detail. (J:90759, J:92092)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Cyp1a1 (rat) Summary of all recombinase alleles driven by Cyp1a1. Comparative matrix view of recombinase activities Alliance rat Cyp1a1 gene page

Tumor Data

List all tumor models in MMHCdb carrying Tg(Cyp1a1-cre)1Dwi

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available

References

• Original: J:92092 Ireland H, et al., Inducible Cre-mediated control of gene expression in the murine gastrointestinal tract: effect of loss of beta-catenin. Gastroenterology. 2004 May;126(5):1236-46
• All: 97 reference(s)