Gys1^{Gt(OST33395)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Gys1^{Gt(OST33395)Lex}
• Name: glycogen synthase 1, muscle; gene trap OST33395, Lexicon Genetics
• MGI ID: MGI:3052742
• Synonyms: Gys1^-, Gys1^{Gt(VICTR25)1Pro}, MGSKO
• Gene: Gys1 Location: Chr7:45084268-45106043 bp, + strand Genetic Position: Chr7, 29.31 cM
• Alliance: Gys1^{Gt(OST33395)Lex} page

Mutation origin

• Mutant Cell Line: OST33395
• Germline Transmission: Earliest citation of germline transmission: J:92245
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• The VICTR25 vector was inserted upstream of exon 12. (J:92245)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  OST33395	CG494480 ; (MGI Seq Detail)	3' RACE	Chr7:45097697-45101338 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  16 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	11 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gys1 Mutation: 57 strains or lines available

References

• Original: J:92245 Pederson BA, et al., Abnormal cardiac development in the absence of heart glycogen. Mol Cell Biol. 2004 Aug;24(16):7179-87
• All: 9 reference(s)