Ppp1r13b^Gt(22A6)Cmhd
Gene trapped Allele Detail

Summary

• Symbol: Ppp1r13b^Gt(22A6)Cmhd
• Name: protein phosphatase 1, regulatory subunit 13B; gene trap 22A6, Centre for Modeling Human Disease
• MGI ID: MGI:3052747
• Synonyms: Ppp1r13b^{Gt(Betageo)1Jrt}
• Gene: Ppp1r13b Location: Chr12:111794891-111874544 bp, - strand Genetic Position: Chr12, 61.14 cM, cytoband F2
• Alliance: Ppp1r13b^Gt(22A6)Cmhd page

Mutation origin

• Mutant Cell Line: 22A6
• Germline Transmission: Earliest citation of germline transmission: J:92259
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Gene trapped (Reporter)
• Mutation: Insertion of gene trap vector Vector: pMS1
• Mutation details: A gene trap vector containing IRES-Betageo-pA was inserted in the 3' UTR. LacZ expression was detected in neural tissues and the epithelium in the lung and intestine. 5' RACE indicated that this is not a loss of function allele. (J:92259)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  CMHD-GT_22A6-3	BZ689855 ; (MGI Seq Detail)	3' RACE	Chr12:111794891-111795025 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  3 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ppp1r13b Mutation: 53 strains or lines available

Notes

This gene trap is no longer available through the Toronto Centre for Phenogenomics.

References

• Original: J:92259 Hirashima M, et al., Gene-trap expression screening to identify endothelial-specific genes. Blood. 2004 Aug 1;104(3):711-8
• All: 1 reference(s)