Tg(LckIl4)1315Dbl
Transgene Detail

Summary

• Symbol: Tg(LckIl4)1315Dbl
• Name: transgene insertion 1315, David Lewis
• MGI ID: MGI:3052795
• Transgene: Tg(LckIl4)1315Dbl Location: unknown
• Alliance: Tg(LckIl4)1315Dbl page

Transgene origin

• Strain of Origin: (C57BL/6J x DBA/2J)F2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(LckIl4)1315Dbl expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Il4 (MGI:96556)

• Mutation details: Transgenic mice overexpress the IL4 transgene under the control of the Lck promoter (lymphocyte protein tyrosine kinase). 8 copies of the transgene were estimated to have integrated into the genome. Expression of the transgene was detected in thymus tissue and by thymocytes. (J:92453)

Expression

In Structures Affected by this Mutation:

8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:92453 Lewis DB, et al., Interleukin 4 expressed in situ selectively alters thymocyte development. J Exp Med. 1991 Jan 1;173(1):89-100
• All: 3 reference(s)