Tg(FABPCFTR)1Jaw
Transgene Detail

Summary

• Symbol: Tg(FABPCFTR)1Jaw
• Name: transgene insertion 1, Jeffrey A Whitsett
• MGI ID: MGI:3052981
• Synonyms: FABP-hCFTR, Tg(FABPCFTR)#Jaw
• Transgene: Tg(FABPCFTR)1Jaw Location: unknown
• Alliance: Tg(FABPCFTR)1Jaw page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(FABPCFTR)1Jaw expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  CFTR (1080)

  Cftr	(MGI:88388)

• Mutation details: The transgene contains rat sequences for the fatty acid-binding protein (FABP) promoter and human sequence for the cystic fibrosis transmembrane conductance regulator homolog (CFTR) gene. Expression of the transgene was abundant in the ileum, jejunum, and duodenum and less abundant in the cecum and the colon. (J:21934)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:21934 Zhou L, et al., Correction of lethal intestinal defect in a mouse model of cystic fibrosis by human CFTR. Science. 1994 Dec 9;266(5191):1705-8
• All: 58 reference(s)