Dspd
Transgenic Allele Detail

Summary

• Symbol: Dspd
• Name: dominant spermiogenesis defect; dominant spermiognenesis defect
• MGI ID: MGI:3052992
• Gene: Dspd Location: unknown
• Alliance: Dspd page

Transgene origin

• Strain of Origin: (C57BL/6 x C3H)F1

Transgene description

• Transgene Type: Transgenic
• Mutations: Intergenic deletion, Translocation
• Mutation details: A transgene insertion resulted in a translocation between chromosomes 7F and 14C and a deletion on chromosome 7C of at least 1 Mb. This deletion contains at least 6 genes including; Cttn, Fadd, Fgf3, Fgf4, Fgf15, and Ccnd1. The transgene contained a chicken Actb promoter, CMV-IE enhancer and a full length human PEG8 cDNA. Expression of the transgene is not thought to be involved in this phenotype. (J:89381)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Dspd Mutation: 1 strain or line available

References

• Original: J:89381 Kai M, et al., The novel dominant mutation Dspd leads to a severe spermiogenesis defect in mice. Biol Reprod. 2004 Apr;70(4):1213-21
• All: 1 reference(s)