Cat^b
Radiation induced Allele Detail

Summary

• Symbol: Cat^b
• Name: catalase; acatalasemia
• MGI ID: MGI:3053604
• Synonyms: Cs^b, M1
• Gene: Cat Location: Chr2:103284249-103315498 bp, - strand Genetic Position: Chr2, 54.43 cM
• Alliance: Cat^b page

Mutation origin

• Strain of Origin: (101 x C3H)F1

Mutation description

• Allele Type: Radiation induced
• Mutation: Nucleotide substitutions
• Mutation details: This allele corresponds to a mutation located in the first alpha helix in the amino terminal arm of the catalase subunit. The substitution of G to T results in an amino acid substitution that replaces glutamine with histidine at position 11. (J:10926)
• Inheritance: Recessive

Disease models

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Cat Mutation: 30 strains or lines available

References

• Original: J:5015 Feinstein RN, et al., Acatalasemic and hypocatalasemic mouse mutants. Genetics. 1966 May;53(5):923-33
• All: 21 reference(s)