Tg(WapIGFBP3)67Dlr
Transgene Detail

Summary

• Symbol: Tg(WapIGFBP3)67Dlr
• Name: transgene insertion 67, Derek LeRoith
• MGI ID: MGI:3053842
• Transgene: Tg(WapIGFBP3)67Dlr Location: unknown
• Alliance: Tg(WapIGFBP3)67Dlr page

Transgene origin

• Strain of Origin: (C57BL/6 x SJL)F2

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(WapIGFBP3)67Dlr expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  IGFBP3 (3486)

  Igfbp3

  (MGI:96438)

• Mutation details: The transgene contains the mouse whey acidic protein promoter followed by the complete open reading frame of the human insulin-like growth factor binding protein 3 gene, including 116 bp of 5'UTR sequence and 523 bp of 3'UTR sequence. (J:92578)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:92578 LeRoith D, et al., Insulin-like growth factor-I and insulin-like growth factor binding protein-3 inhibit involution of the mammary gland following lactation: studies in transgenic mice. Prog Growth Factor Res. 1995;6(2-4):433-6
• All: 2 reference(s)