Tg(WapTgfa)215Bri
Transgene Detail

Summary

• Symbol: Tg(WapTgfa)215Bri
• Name: transgene insertion 215, Ralph L Brinster
• MGI ID: MGI:3054253
• Synonyms: TgN(WapTgfa)215Bri, WAP-TGF-alpha line 3573-2
• Transgene: Tg(WapTgfa)215Bri Location: unknown
• Alliance: Tg(WapTgfa)215Bri page

Transgene origin

• Strain of Origin: (C57BL/6 x SJL)F2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(WapTgfa)215Bri expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  rat

  Tgfa (24827)

  Tgfa	(MGI:98724)

• Mutation details: The transgene contains the mouse whey acidic protein (WAP) promoter and the mouse transforming growth factor alpha (Tgfa) gene. (J:56318)

Disease models

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Tumor Data

List all tumor models in MMHCdb carrying Tg(WapTgfa)215Bri

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:56318 Sandgren EP, et al., Inhibition of mammary gland involution is associated with transforming growth factor alpha but not c-myc-induced tumorigenesis in transgenic mice. Cancer Res. 1995 Sep 1;55(17):3915-27
• All: 7 reference(s)