Rnu2-8^nmf291
Chemically induced Allele Detail

Summary

• Symbol: Rnu2-8^nmf291
• Name: U2 small nuclear RNA 8; neuroscience mutagenesis facility, 291
• MGI ID: MGI:3054730
• Gene: Rnu2-8 Location: unknown Genetic Position: Chr11, Syntenic
• Alliance: Rnu2-8^nmf291 page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:87349
• Parent Cell Line: v6.4 (ES Cell)
• Strain of Origin: (C57BL/6J x 129S4/SvJae)F1

Mutation description

• Allele Type: Chemically induced (other)
• Mutation: Intragenic deletion
• Mutation details: This phenotypic allele was identified in an ethylmethanesulfonate (EMS) mutagenesis screen for neurological phenotypes. The molecular defect is a 5 base pair deletion between nucleotides 30 and 34 in a highly conserved region located in the U2 consensus branch site sequence (BSRS) and the linker region between the BSRS and the U2/U6 helix. (J:179357)
• Inheritance: Recessive

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Rnu2-8 Mutation: 1 strain or line available

References

• Original: J:87349 JAX Neuroscience Mutagenesis Facility, Heritable mouse mutants from JAX NMF ENU Mutagenesis Program. MGI Direct Data Submission. 2004-7
• All: 3 reference(s)