Npas3^tm1Slm
Targeted Allele Detail

Summary

• Symbol: Npas3^tm1Slm
• Name: neuronal PAS domain protein 3; targeted mutation 1, Steven l McKnight
• MGI ID: MGI:3054783
• Synonyms: Npas3-
• Gene: Npas3 Location: Chr12:53294940-54118958 bp, + strand Genetic Position: Chr12, 22.31 cM, cytoband C1
• Alliance: Npas3^tm1Slm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:92610
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Not Specified
• Immunohistochemistry confirms the absence of protein expression in the CNS in homozygotes. (J:92610)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Npas3 Mutation: 41 strains or lines available

References

• Original: J:92610 Erbel-Sieler C, et al., Behavioral and regulatory abnormalities in mice deficient in the NPAS1 and NPAS3 transcription factors. Proc Natl Acad Sci U S A. 2004 Sep 14;101(37):13648-53
• All: 6 reference(s)