Tg(PLTP)1Pgn
Transgene Detail

Summary

• Symbol: Tg(PLTP)1Pgn
• Name: transgene insertion 1, Beverly Paigen
• MGI ID: MGI:3054872
• Synonyms: Line A
• Transgene: Tg(PLTP)1Pgn Location: unknown
• Alliance: Tg(PLTP)1Pgn page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(PLTP)1Pgn expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  PLTP (5360)

  Pltp	(MGI:103151)

• Mutation details: The transgene contains the human phospholipid transfer protein (PLTP) and 4.3 kb of its native 5' flanking region. PTLP mRNA transcripts were found in adipose tissue, lung, heart, and spleen of transgenic mice. (J:92804)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:92804 Albers JJ, et al., Transgenic mice expressing human phospholipid transfer protein have increased HDL/non-HDL cholesterol ratio. Int J Clin Lab Res. 1996;26(4):262-7
• All: 2 reference(s)