Tg(APOC2)2Bres
Transgene Detail

Summary

• Symbol: Tg(APOC2)2Bres
• Name: transgene insertion 2, Jan L Breslow
• MGI ID: MGI:3054893
• Synonyms: apoC-II, CII
• Transgene: Tg(APOC2)2Bres Location: unknown
• Alliance: Tg(APOC2)2Bres page

Transgene origin

• Strain of Origin: (C57BL/6J x CBA/J)F2

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(APOC2)2Bres expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  APOC2 (344)

  Apoc2	(MGI:88054)
  Apoc2l	(MGI:5753381)

• The transgenic construct contains the human APOC2 gene and the human CYP1A1 promoter. (J:81186)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available

References

• Original: J:81186 Shachter NS, et al., Overexpression of apolipoprotein CII causes hypertriglyceridemia in transgenic mice. J Clin Invest. 1994 Apr;93(4):1683-90
• All: 2 reference(s)