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GabpaGt(XH074)Byg
Gene trapped Allele Detail
Summary
Symbol: GabpaGt(XH074)Byg
Name: GA repeat binding protein, alpha; gene trap XH074, BayGenomics
MGI ID: MGI:3054951
Synonyms: GabpaGt(pGT1Lxf)1Wjl, Gabpatp
Gene: Gabpa  Location: Chr16:84631813-84660667 bp, + strand  Genetic Position: Chr16, 46.92 cM, cytoband C3-4
Alliance: GabpaGt(XH074)Byg page
Mutation
origin
Mutant Cell Line:  XH074
Germline Transmission:  Earliest citation of germline transmission: J:92671
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Gene trapped (Null/knockout, Reporter)
Mutation:    Insertion of gene trap vector     Vector: pGT1Lxf     Vector Type: gene trap
 
Mutation detailsXH074 ES cells contain an insertion of Beta-galactosidase-encoding vector pGT1Lxf in intron V of Gapba. ES cells were injected into C57BL/6 blastocysts. (J:92671)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 17 assay results
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gabpa Mutation:  67 strains or lines available
Notes
All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.
References
Original:  J:92671 Xue HH, et al., GA binding protein regulates interleukin 7 receptor alpha-chain gene expression in T cells. Nat Immunol. 2004 Oct;5(10):1036-44
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory