Tg(PRG1)18Wlad
Transgene Detail

Summary

• Symbol: Tg(PRG1)18Wlad
• Name: transgene insertion 18, Wyeth Lederle/Anne Deatly
• MGI ID: MGI:3055287
• Synonyms: PRG1, TGM-PRG-1
• Transgene: Tg(PRG1)18Wlad Location: unknown
• Alliance: Tg(PRG1)18Wlad page

Transgene origin

• Strain of Origin: (C57BL/6J x CBA/J)F1

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(PRG1)18Wlad expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  PVR (5817)

  Pvr	(MGI:107741)

• Mutation details: This line carries one copy of the human poliovirus receptor transgene (PVR). The human polio virus receptor is a member of the Igg superfamily. Northern and Western blot analyses of tissues from transgenic mice detected expression of the transgene at levels one third of levels detected in tissues from transgenic mice carrying ten copies of human PVR. (J:92990)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:92990 Deatly AM, et al., Characterization of mouse lines transgenic with the human poliovirus receptor gene. Microb Pathog. 1998 Jul;25(1):43-54
• All: 2 reference(s)