Hpca^tm1Toho
Targeted Allele Detail

Summary

• Symbol: Hpca^tm1Toho
• Name: hippocalcin; targeted mutation 1, Toho University
• MGI ID: MGI:3055313
• Gene: Hpca Location: Chr4:129005363-129015829 bp, - strand Genetic Position: Chr4, 62.88 cM, cytoband D2-D3
• Alliance: Hpca^tm1Toho page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:97752
• Parent Cell Line: CCE/EK.CCE (ES Cell)
• Strain of Origin: 129S/SvEv-Gpi1^c

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: A neo was inserted into intron 1. Western blot and immunocytochemistry confirmed absence of protein in mutants. (J:97752)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Hpca Mutation: 12 strains or lines available

References

• Original: J:97752 Korhonen L, et al., Hippocalcin protects against caspase-12-induced and age-dependent neuronal degeneration. Mol Cell Neurosci. 2005 Jan;28(1):85-95
• All: 5 reference(s)