Summary |
|
||||||||||||
Mutation origin |
|
||||||||||||
Mutation description |
|
||||||||||||
Phenotypes |
![]()
View phenotypes and curated references for all genotypes (concatenated display).
|
||||||||||||
Expression |
|
||||||||||||
Find Mice (IMSR) |
|
||||||||||||
Notes |
ES cell line EB3/5 is a mutant E14TG2a line carrying one inactivated allele of Pou5f1.
Rescue of placental defects by complementation with tetraploid embryos extends survival up to at least E13.5. These rescued mutant mice have a normal heart, exhibit normal placental development and grow as well as wild-type embryos. |
||||||||||||
References |
|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 08/21/2024 MGI 6.24 |
![]() |
|