Tg(SLC2A4-OGT)15Jaha
Transgene Detail

Summary

• Symbol: Tg(SLC2A4-OGT)15Jaha
• Name: transgene insertion 15, John A Hanover
• MGI ID: MGI:3055948
• Transgene: Tg(SLC2A4-OGT)15Jaha Location: unknown
• Alliance: Tg(SLC2A4-OGT)15Jaha page

Transgene origin

• Strain of Origin: Not Applicable

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(SLC2A4-OGT)15Jaha expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  OGT (8473)

  Ogt	(MGI:1339639)

• Mutation details: The human SLC2A4 promoter drives expression of human OGT in the adipose tissue and cardiac and skeletal muscle. Five transgenic lines were generated with most studies using lines 15, 26, and 32. This is a representative record where unspecified lines among Tg15, Tg18, Tg23, and Tg32 were used in determining phenotype. (J:93113)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:93113 McClain DA, et al., Altered glycan-dependent signaling induces insulin resistance and hyperleptinemia. Proc Natl Acad Sci U S A. 2002 Sep 6;99(16):10695-9
• All: 1 reference(s)