Ndufa13^tm1Xc
Targeted Allele Detail

Summary

• Symbol: Ndufa13^tm1Xc
• Name: NADH:ubiquinone oxidoreductase subunit A13; targeted mutation 1, Xinmin Cao
• MGI ID: MGI:3056073
• Synonyms: Grim19^-
• Gene: Ndufa13 Location: Chr8:70346830-70355208 bp, - strand Genetic Position: Chr8, 34.03 cM, cytoband C1
• Alliance: Ndufa13^tm1Xc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:93022
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• The entire coding region was replaced by a neomycin resistance gene. (J:93022)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ndufa13 Mutation: 13 strains or lines available

References

• Original: J:93022 Huang G, et al., GRIM-19, a cell death regulatory protein, is essential for assembly and function of mitochondrial complex I. Mol Cell Biol. 2004 Oct;24(19):8447-56
• All: 2 reference(s)