Ctnnb1^tm1.1Yy
Targeted Allele Detail

Summary

• Symbol: Ctnnb1^tm1.1Yy
• Name: catenin beta 1; targeted mutation 1.1, Yingzi Yang
• MGI ID: MGI:3056114
• Synonyms: Catnb^-
• Gene: Ctnnb1 Location: Chr9:120762466-120789573 bp, + strand Genetic Position: Chr9, 72.19 cM
• Alliance: Ctnnb1^tm1.1Yy page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:93028
• Parent Cell Line: TC1/TC-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Catnb^tm1Yy mice were crossed with mice expressing Cre in the germline, thereby producing an allele in which exons 3 through 6 were deleted. (J:93028)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ctnnb1 Mutation: 49 strains or lines available

References

• Original: J:93028 Guo X, et al., Wnt/beta-catenin signaling is sufficient and necessary for synovial joint formation. Genes Dev. 2004 Oct 1;18(19):2404-17
• All: 2 reference(s)