Tg(Myh6-NFATC4)#Eno
Transgene Detail

Summary

• Symbol: Tg(Myh6-NFATC4)#Eno
• Name: transgene insertion, Eric N Olson
• MGI ID: MGI:3056187
• Transgene: Tg(Myh6-NFATC4)#Eno Location: unknown
• Alliance: Tg(Myh6-NFATC4)#Eno page

Transgene origin

• Strain of Origin: FVB

Transgene description

• Transgene Type: Transgenic (Constitutively active, Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The promoter region of Myh6 drives expression of a constitutively active NFATC4 mutant that lacks the first 317 amino acids containing the N-terminal regulatory domain but retains the REL homology and transactivation domains. Three lines were generated that all have identical phenotypes. (J:93176)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:93176 Molkentin JD, et al., A calcineurin-dependent transcriptional pathway for cardiac hypertrophy. Cell. 1998 May 17;93(2):215-28
• All: 6 reference(s)