Foxf2^W174R
Chemically induced Allele Detail

Summary

• Symbol: Foxf2^W174R
• Name: forkhead box F2; Trp174Arg
• MGI ID: MGI:3056482
• Synonyms: GSK 14H3
• Gene: Foxf2 Location: Chr13:31809799-31815386 bp, + strand Genetic Position: Chr13, 13.48 cM, cytoband A4
• Alliance: Foxf2^W174R page

Foxf2^W174R/Foxf2^W174R pups are smaller at 3 days after birth and consume less milk at birth

Show the 5 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: (C3H/HeH x BALB/c)F1

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a T to A transversion that results in the amino acid substitution of arginine for tryptophan at position 174 (W174R). (J:93069)

Expression

In Structures Affected by this Mutation:

9 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Foxf2 Mutation: 21 strains or lines available

Notes

Phenotypic Similarity to Human Syndrome: Anterior segment dysgenesis in homozygous mice (J:178103)

References

• Original: J:93069 Quwailid MM, et al., A gene-driven ENU-based approach to generating an allelic series in any gene. Mamm Genome. 2004 Aug;15(8):585-91
• All: 2 reference(s)