Slc30a1^tm1Gka
Targeted Allele Detail

Summary

• Symbol: Slc30a1^tm1Gka
• Name: solute carrier family 30 (zinc transporter), member 1; targeted mutation 1, Glen K Andrews
• MGI ID: MGI:3056498
• Gene: Slc30a1 Location: Chr1:191638879-191645359 bp, + strand Genetic Position: Chr1, 97.01 cM
• Alliance: Slc30a1^tm1Gka page

Slc30a1^tm1Gka/Slc30a1^tm1Gka embryos fail to undergo early morphogenesis

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:93193
• Parent Cell Line: AB1 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1⁺

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 1 and part of exon 2 were replaced by a Beta-geo, deleting the first 348 amino acids (out of 503). Beta-gal activity is observed in late gestation fetuses. (J:93193)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc30a1 Mutation: 14 strains or lines available

References

• Original: J:93193 Andrews GK, et al., Mouse zinc transporter 1 gene provides an essential function during early embryonic development. Genesis. 2004 Oct;40(2):74
• All: 1 reference(s)