Igbp1^tm1Cbt
Targeted Allele Detail

Summary

• Symbol: Igbp1^tm1Cbt
• Name: immunoglobulin (CD79A) binding protein 1; targeted mutation 1, Craig B Thompson
• MGI ID: MGI:3056510
• Synonyms: alpha4^fl
• Gene: Igbp1 Location: ChrX:99537897-99559731 bp, + strand Genetic Position: ChrX, 43.72 cM
• Alliance: Igbp1^tm1Cbt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:93221
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• LoxP sites were inserted around exons 3-5 via homologous recombination. (J:93221)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Igbp1 Mutation: 9 strains or lines available

References

• Original: J:93221 Kong M, et al., The PP2A-associated protein alpha4 is an essential inhibitor of apoptosis. Science. 2004 Oct 22;306(5696):695-8
• All: 1 reference(s)