Crebbp^tm1.1Ltz
Targeted Allele Detail

Summary

• Symbol: Crebbp^tm1.1Ltz
• Name: CREB binding protein; targeted mutation 1.1, Beat Lutz
• MGI ID: MGI:3056562
• Synonyms: CBP^stop523
• Gene: Crebbp Location: Chr16:3899198-4031864 bp, - strand Genetic Position: Chr16, 2.4 cM
• Alliance: Crebbp^tm1.1Ltz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:93192
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Cre mediated recombination of the flanking loxP sites results in the deletion of exon 2 from Crebbp^tm1Ltz, generating a stop codon in the open reading frame at the beginning of exon 3. (J:93192)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Crebbp Mutation: 100 strains or lines available

References

• Original: J:93192 Zhang Z, et al., Generation of a conditional allele of the CBP gene in mouse. Genesis. 2004 Oct;40(2):82
• All: 1 reference(s)