Crebbp^tm1.2Ltz
Targeted Allele Detail

Summary

• Symbol: Crebbp^tm1.2Ltz
• Name: CREB binding protein; targeted mutation 1.2, Beat Lutz
• MGI ID: MGI:3056564
• Synonyms: CBP^fl
• Gene: Crebbp Location: Chr16:3899198-4031864 bp, - strand Genetic Position: Chr16, 2.4 cM
• Alliance: Crebbp^tm1.2Ltz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:93192
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Flp mediated recombination of the flanking frt sites results in the deletion of the neo cassette from Crebbp^tm1Ltz, leaving exon 2 flanked with loxP sites. (J:93192)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Crebbp Mutation: 100 strains or lines available

References

• Original: J:93192 Zhang Z, et al., Generation of a conditional allele of the CBP gene in mouse. Genesis. 2004 Oct;40(2):82
• All: 11 reference(s)